![]() Retrospective analysis of the clinical records of patients under the age of 21 years with molecularly confirmed CS followed at the Rare Disease Unit, Paediatrics Department, Fondazione Policlinico Agostino Gemelli-IRCCS, Rome, between 20 allowed to identify 16 subjects (8 M age range 4–21 years mean 11 years DS 6 years median 10 years), all reported to have feeding difficulties. Given the clinical relevance of these aspects, here, we retrospectively collected the data on feeding and swallowing abilities that had systematically been recorded in a relatively large, single-centre CS cohort to evaluate the evolution of the feeding and swallowing abilities with age. Īlthough feeding problems and swallowing issues have already been investigated in CS, there is no clear understanding of the skill progression according to age, and longitudinal data are lacking. Poor oral intakes may have unfavourable outcome on bone mineralization and growth during childhood and severe gastroesophageal reflux may imply the placement of a gastrostomy tube and the consequent exclusion of mouth feeding. ![]() In the majority of cases (> 80%), magnetic resonance imaging demonstrated the absence or hypoplasia of olfactory bulbs and sulci with a consequent or completely absent sense of smell. Moreover, surgical procedures to repair structural anomalies, including cleft lip/palate and choanal atresia, can postpone the introduction of oral feeding. Specifically, the ability to suck, swallow or chew can be ineffective or absent due to cranial nerve dysfunction. Prematurity, neurological impairment, long-term tube feeding and limited experiences with oral intake often result in a limited progression of child’s oral motor skills. According to Stromland et al., children with CS may experience persistent drooling (25%), resulting in a further negative factor on feeding abilities. ![]() įeeding problems and swallowing dysfunction have been reported as a common feature in CS, and over 90% individuals need artificial nutrition during their life. CS is an autosomal dominant disorder caused by loss-of-function variants in CHD7 or deletions of the gene within chromosome region 8q12, and previous studies reported the detection of pathogenic variants in 70–90% of clinically diagnosed CS cases. The acronym CHARGE was first suggested by Pagon et al. ĬS was first recognized by Hall and Hittner and, hence, it was initially called Hall-Hittner syndrome. Minor diagnostic criteria include orofacial cleft (frequent), distinctive facial appearance, tracheoesophageal fistula (occasional), limb abnormalities (occasional) and rarely immune deficiencies. The visual system is invariably affected, with an association between hypomorphic variants and milder ophthalmological features. The acronym ‘CHARGE’ describes the constellation of cardinal features characterizing the disorder, including coloboma (very frequent), heart defects (frequent), choanal atresia (frequent), retardation of growth (frequent) and/or development (very frequent), genitourinary malformation (very frequent for male, frequent for female) and external ear abnormalities (very frequent). Rehabilitation plays a key role in overcoming structural and functional difficulties and attaining appropriate eating skills.ĬHARGE syndrome (CS) (OMIM #214,800) is a rare congenital disorder with an incidence that ranges from 0.1 to 1.2/10,000 live births. Most patients started prolonged oral-motor treatments with speech language therapists in early childhood.Ĭonclusions: Although feeding and swallowing disorders are constant features in CS patients, a slow and gradual development of feeding abilities occurs in most cases. ![]() A mature chewing pattern with a variety of food textures was not achieved by more than half of patients, including those requiring artificial enteral nutrition. The ability of eating foods requiring chewing was achieved at school age, after the acquisition of an adequate oral sensory processing. Over time, the percentages of children with tube feeding dependence (60% at birth) faced a slow but steady decrease (from 33% at 6 months, 25% at 12 months, to 13% at school age) in tandem with the decreasing risk of aspiration. Nearly 100% of CS new-borns had weak sucking at birth, and half of them demonstrated poor coordination between breathing and swallowing. We retrospectively analysed oral-motor features of 16 patients with molecularly confirmed CS (age range 4–21 years old mean 11 years SD 6 years median 10 years). This study aims to investigate the level of these abilities at different ages and evaluate how they evolve during growth. To date, the feeding and oral-motor abilities of patients with CHARGE syndrome (CS) have not been longitudinally assessed. ![]()
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![]() ![]() My Evergoods cpl24 Phoenix and tumi Nathan leather are my compact EDC. Some people use a 34L gr2 and TP2 as an EDC. On sizing, really depends, some people use 30-35 liters as their daily carry if they haul a ton of stuff, mainly packing cubes with clothes. ![]() It's the perfect iteration of their Kickstarter backpack with dem magnetics baby. The new TP3 changes makes it super enticing. Bo Ismono reviewed the TP1 a few years ago (time flies), he's 5'7 I believe. Traveling Salseros on YouTube has a great review on the travel pack 2 and he's 5'11. I got to try the TP2 at Bloomingdales back in 2019. I'm 5'7 and I think the Goruck Gr2 and Aer Travel Pack 2 have looked fine on my back. I think you'd be better work the Aer Travel Pack 3 Small 28L if you plan on using it as a day bag. For EDC I think the Travel Pack 3 would be too big. Protect your backpack and gear from the elements. Now you can get your favoriate product without any hesitation because of the amazing price, no Aersf voucher code or discount code need. Length: 21.5' (54.5 cm) Width: 13' (33 cm) Depth: 9' (21.5 cm) Lightweight Water-Resistant Protection Discover the all-new Rain Cover Large. Grab this great discount & deal before its gone. Travel Backpack for Men Women 17 Inch Flight Approved Carry on Backpack Waterproof Large 40L Luggage Daypack Business College Weekender Overnight Laptop Backpack with 3 Packing Cubes, Black. ![]() I don't own an Aer TP2, however I do use a Goruck 34L Kaidan Carryology GR2. Incredible special offer: Travel Pack 220. I only found that if you overpack their bags, like any bag beyond its true carry, any strap can become a nuisance, and even these dug mercilessly into my traps. Also, their bags allow more room for adjustment where you can wear them lower. The rucker 3.0 i had seemed to let me carry anything i thru at it.īut if you just want a softer than soft strap, tom bihn gets my vote. The straps are the worst in terms of comfort but when cinched close to the body, the pack rigidity almost becomes a part of you, locking your load right to your body, making the overall experience much more comfortable for large load carry. Its that carry experience that made me a manybagger!! Wearing it low completely defeats that purpose. The Fit Pack 3 stores your gym/work essentials without adding extra bulk. evergoods bags are designed to sit very high on the body and cinching the bag up only really unlocks its true potential in comfort. The aer straps are of the best ive used and find them very comfortable among tom bihn, evergoods, and able carry bags i own.īut keep in mind, straps are only a part of the equation to the overall design of a nice bag.Į.g. ![]() ![]() ![]() A unique locking mechanism in the base keeps the whole unit safe and secure. ![]() The QR code on the seat leads you to helpful tutorial videos for two installation options: seat belt and tether, or lower anchor and tether, also known as LATCH. Installing the Evenflo Gold Revolve360 is straightforward and took us only 12 minutes on the first try. We loved being able to rotate the seat one-handed while still holding a child in the other hand. To rotate, pull up one of the levers on either side of the car seat and spin it until you hear it click into place. This rotating car seat swivels effortlessly 360 degrees to get a child in or out in all modes, including rear-facing (4 to 40 pounds), forward-facing (22 to 65 pounds), and high-back booster (40 to 120 pounds). The rotating capability, straightforward installation, and many safety features of the Evenflo Gold Revolve360 Convertible Car Seat blew us away. Rear-facing recline sometimes impacts driver/passenger seat We will update this list as our editors provide additional feedback to ensure we recommend the best convertible car seats. Our editors and their kids continue to use these convertible car seats in their daily routines to help determine their long-term quality and durability. We also cleaned each car seat according to the manufacturer’s recommendations when needed.Īfter thorough testing, we chose the 14 best convertible car seats to feature in our article. We used the convertible car seats almost daily during the initial four-week testing period to determine ease of use, durability, and safety. After completing the installation, we placed our children into the car seats and secured the harnesses, positioning the chest clips just below their armpits before tightening them to fit. We then wiggled the seats from side to side and front to back to ensure we followed the 1-inch rule (the seat should not move more than 1 inch in any direction). Next, we set a timer and installed each convertible car seat using both the seat belt and LATCH systems. ![]() ![]() When testing convertible car seats, we first unboxed them and reviewed the instruction manuals to ensure proper installation. We then narrowed our list down to 22 convertible car seats that met all of our criteria, and sent them home with our parenting editors to test in their own vehicles with their children ages 4 months to 4 years old. With this guidance in mind, we researched dozens of top-rated convertible car seats in the market and considered their design, safety features, and value. A family physician on our Review Board also reviewed this article for medical accuracy and integrity around the importance of car seat safety, like seating positions, safety harnesses, and more. We also spoke to parents and medical professionals, including Benjamin Hoffman, MD, AAP president-elect and nationally recognized child injury prevention and education expert, and Alisa Baer, MD, pediatrician and co-founder of The Car Seat Lady, LLC. To find the best convertible car seats, we researched safety guidelines issued by the American Academy of Pediatrics (AAP), the National Highway Traffic Safety Administration (NHTSA), and the Federal Aviation Administration (FAA). 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Tins and jars can serve both a functional and a decorative purpose.ĭecorative containers can be used for storing small items, such as jewellery or trinkets, or as packaging for gifts such as candles, soaps, or other small items. We offer a wide range of mason jars, food containers and glass jars of different shapes, sizes and colours, so you can keep everything tidy in your cupboards and cabinets and easy to find. Typically sealed with a lid, which can be either a screw-on or a snap-on, these handy containers are an eco-friendly alternative that can help keep your perishables fresh for longer periods of time and can reduce the need for disposable plastic containers or packaging. The key difference between jars and tins is their material: while jars are typically made of glass or plastic, tins are typically made of metal, such as aluminium or steel. By making it easier to see what items are available and what needs to be restocked, clear jars and tins can inspire you to cook more often and experiment with new recipes. In kitchens and pantries, this is the most efficient way to make the best use of all your storage jars and tins while showcasing the ingredients themselves. What better to reduce waste and organise the clutter in your home than by reorganising your shelves and cabinets with jars and tins? Tips to improve the quality of your sleep this summer.Storage & organisation Furniture Outdoor living Textiles Beds & mattresses Baby & children Kitchenware & tableware Lighting Kitchens Decoration Bathroom products Rugs, mats & flooring Smart home Plants & plant pots Laundry & cleaning Home electronics Summer Working from home Home improvement Food & beverages Shop by room ![]() ![]() ![]() The last three of the seven volumes contain oversights and fragmentary or unpolished passages, as they existed only in draft form at the death of the author the publication of these parts was overseen by his brother Robert.' ***Marcel Proust was best known for this 3200 page masterpiece, originally published as "A La Recherche du Temps Perdu", and first translated into English by C.K. Proust established the structure early on, but even after volumes were initially finished, he continued to add new material and edited one volume after another for publication. ![]() Proust continued to work on it until his final illness in the autumn of 1922 forced him to break off. "In Search of Lost Time" follows the narrator's recollections of childhood and experiences into adulthood in the late 19th-century and early 20th-century high-society France, while reflecting on the loss of time and lack of meaning in the world. Enright adopted it for his revised translation published in 1992. Scott Moncrieff as "Remembrance of Things Past", but the title "In Search of Lost Time", a literal rendering of the French, became ascendant after D. The novel gained fame in English translation by C. The most famous example of this is the "episode of the madeleine", which occurs early in the first volume. This early 20th-century work is his most prominent, known both for its length and its theme of involuntary memory. ***'"In Search of Lost Time", first translated into English as "Remembrance of Things Past", and sometimes referred to in French as "La Recherche" (The Search), is a novel in seven volumes by French author Marcel Proust. ***Volume one is numbered copy 701 of 'two thousand tw***Each volume is a uniform size of 194mm x 138mm except "Time Regained" which is slightly taller at 212mm. 1 of "Swann's Way" also has some details of where the books were purchased in pencil. ***The volumes of "Swann's Way" and "Within a Budding Grove" each have the bookplate of the Duchess of Westminster - Vol. Internally also very good with no creases or tears to the pages. Top edges of the page blocks of some volumes are stained blue by the publisher to match the boards. Head and tail of spines slightly rubbed and creased. Boards slightly rubbed and marked commensurate with age and handling. ***ALL VOLUMES - very good to near fine in blue cloth-covered boards with gilt titles to the spines. "Cities of the Plain" and "Time Regained" are limited editions. The books are published either by Chatto & Windus or Alfred A Knopf. All volumes translated from the French by C. A complete set of eleven volumes in First UK edition, published between 19 - all first impressions of the first editions in English, except for the two volumes of "Swann's Way" which are fourth impressions published in August 1925. INTERNATIONAL AND PRIORITY ORDERS REQUIRE ADDITIONAL SHIPPING CHARGES. ATTENTION: THIS IS A VERY HEAVY AND OVERSIZE SET. The cover of all volumes looks identical except the volume number. Some wear along the edges, tips, and along the spine. Selected pages may contain light wrinkles and creases to edges. 402 pages / All volumes: Some discoloration to pages and inside covers. 563 pages / Volume IV - The Sweet Cheat Gone. 352 pages / Volume III - Cities of The Plain, Volume Two. 356 pages / Volume II - The Guermantes Way: Cities of The Plain, Volume One. ![]() Titles include: Volume I - Swann's Way: Within A BUdding Grove. This set is a translation of the eight-volume work, A la Recherche due Temps Perdu, by Marcel Proust. The cause of death has not been released (as of 2021).Hardcover. On a California Supreme Court judge officially sentenced Franklin to death. The jury also requested the death penalty for Franklin. Franklin was eventually identified and arrested in July 2010 he was tried and convicted of 10 counts of murder in the first degree and one count of attempted murder in the first degree. Franklin's victims weren't linked until May of 2007 when D.N.A. 25 Auto, but he went undiscovered due to a forensics mistake matching the bullets to a Deputy Sheriff's backup weapon. Franklin killed his victims by shooting them he preferred to use a. had little interest in investigating the murders it wasn't until the community pressured them that they began investigating. Shortly after, he started raping and killing prostitutes and drug users, but at the time the L.A.P.D. He first started killing shortly after his release from military prison in 1985 he had been serving a 10 year sentence for raping a 16-year-old girl in Germany while he was stationed there in the U.S. who operated in Los Angeles from 1985 to 1988 and again from 2002 to 2010, which led to his title being given to him by the press because his killing spree stopped for 14 years. The Grim Sleeper was a name given to real-life serial killer Lonnie David Franklin Jr. ![]() ![]() ![]() Modern menu plans and eating practices, even when expanded and extended for the purposes of holiday celebration, tend to follow a fairly straightforward appetizer-entrée-dessert trajectory that lasts maybe an hour or two around the actual table. In the recipe for a medieval feast, time is the essential ingredient.īy medieval weights and measures, we simply don’t spend enough time at the dinner table. Although rarely used, plates, rather than trenchers, may appear here, as the individual dishes are the same color as the serving platters, or chargers, on the table. ![]() Medieval illumination depicting a feast for King Richard II of England, who reigned from 1377 to 1399 (BL Royal MS 14 E IV, f. Indeed, the staging and procession of the meal was as crucial for a successful feast as the food. Music not only created appropriate atmosphere for the meal but also signaled the start of each course, even the introduction of specific dishes. Performers of various kinds popped from enormous puddings, enacting a grand entrance that was itself a form of entertainment.Īs guests imbibed in food and drink, musicians provided vocal and instrumental accompaniment to the feast. Mythical creatures from medieval bestiaries, such as the cockentrice, were created by cooks who stitched together the upper half of a chicken and the lower half of a pig or vice versa. Live birds were tethered in pies so that they sang when the crust was cut. Peacocks, a medieval delicacy, were cooked and served readorned with their iridescent feathers. Pageantry was an integral component of the medieval feast. Depicted beside the beginning of her tale in the fifteenth-century Ellesmere Chaucer, the Prioress may have questionable morals, but her table etiquette could not be more dignified (Huntington Library, San Marino, MSS EL 26 C 9, f. The General Prologue describes how during meals the Prioress lets no morsel fall from her lips, does not dip her fingers too deeply into sauces, carries her food seamlessly to mouth, and ensures no grease enters her cup while drinking (lines 127-136). The Prioress, one of the pilgrims from Geoffrey Chaucer’s Canterbury Tales, exhibits the the extent to which manners mattered in the Middle Ages. Hands were washed in perfumed water before the meal began, between courses, and at the meal’s end. Particular fingers were used for particular foods to avoid tampering. Napkins were pinned around the neck or placed in the lap. On the contrary, table manners were held in high regard, as was hygiene. The lack of utensils does not indicate a lack of etiquette. A knife, frequently one of their own, would be used for lifting meats from platters and sometimes to the mouth. Medieval diners would have primarily used their fingers, plus a spoon supplied by their host for soft foods such as soups and puddings. The image, contained in a manuscript produced in France and illuminated in England in the early 14th century and housed at the British Library, depicts two men baking bread (BL Royal MS 10 E IV, f. Trenchers were often colored with spices: rendered green with parsley, yellow with saffron, and pink with sandalwood. Not unlike contemporary bread bowls, trenchers were, essentially, edible crockery. For example, while we pile food upon plates and tuck into our dinners with a fork, our predecessors preferred a hearty slab of bread and a spoon.īread was not only served for eating but also used as crockery: large, typically square slices of bread called trenchers were used in place of dishes and, after absorbing drippings from the feast, were refurbished as sop in wine or milk or given as alms to the poor. Like the feasting accoutrements of medieval England, contemporary Christmas table settings typically include cloths and candles, serving platters and salt, a plethora of foods to sample and savor. But modern feasts are minuscule meal events by medieval standards. ![]() Pairing myriad traditional dishes with more elaborate fare in a spectacle appealing to both sight and stomach, the modern Christmas meal maintains some semblance of the medieval feast. ![]() ![]() ![]() According to Rolling Stone writer Ryan Reed, the lyrics consist of "praising one particular set of lips", "setting the scene with lots of specific imagery". "Good Kisser" is an uptempo "stripped-back soul-funk" R&B song that has a "sensuous, sturdy bassline", "salsa drums", a "dusty vinyl pops", '" Rich Harrison-recalling" "cowbell-heavy percussion", "jazzy keyboards", "handclaps" and Usher's "loose vocal delivery". Usher made some lyrical changes to the song, including the change of the word "suck" to "kiss" in order to make the song less "X-rated". Pop later went to a Los Angeles studio to show the song to Mark Pitts, who later gave it to Usher for him to perform. ![]() Later that night, I went to the studio and just put it all down, then forgot about it. So I woke up one morning just singing 'Don't nobody kiss it like you baby,' and I was just singing it all day long. ![]() ".a lot of times when I wake up singing something random, it turns into a song. In an interview, Pop discussed how the song was conceived: It was produced by Pop Wansel, with co-production handled by Ronald "Flippa" Colson, JProof, Terry "Tru" Sneed, Natural and Oak Felder. "Good Kisser" was written by Andrew "Pop" Wansel, Ronald "Flippa" Colson, Jameel Roberts, Terry Sneed and Warren "Oak" Felder, with co-writing done by Usher. The official remix features an additional verse from Rick Ross. The latter declared that his next album would show that he is "still Usher". Bellinger compared the album's music to Usher's Confessions (2004), saying that it is "more R&B, more urban" than Usher's Looking 4 Myself. In an interview with Eric Bellinger by Rap-Up, the former explained that he, along with Jermaine Dupri, Bryan-Michael Cox, and Brian Alexander Morgan, were working on Usher's next album. Talking to The Fader, he described the album as "everything you can imagine", saying that it's "gonna be freaking out of here". "Good Kisser" was supposed to be a track from his upcoming eighth studio album, Flawed, which Usher announced was in the works on March 19, 2013. It was nominated for Best R&B Song and Best R&B Performance at the 57th Annual Grammy Awards. "Good Kisser" was ranked at number two on Billboard 's "10 Best R&B Songs on 2014" list. It also charted in Australia, Flanders, France, Germany, the Netherlands and South Korea. In North America, the song reached number 65 on the US Billboard Hot 100, number one on the Hot R&B/Hip-Hop Airplay chart, and number 14 on the Rhythmic Songs chart. Originally intended to be the lead single from his eighth studio album, Hard II Love, the song was scrapped from the standard edition track listing, with the track only being included on the Japanese edition of the album. The song was written by Andrew "Pop" Wansel, Bobby Bloom, Jeff Barry, Ronald "Flippa" Colson, Jameel Roberts, Terry Sneed and Warren "Oak" Felder, with co-writing done by Usher, produced by Pop Wansel and Co-produced by Ronald "Flippa" Colson, Jproof, Terry "Tru" Sneed, Natural and Oak Felder. The accompanying music video debuted the same day. The single was released on May 5, 2014, by RCA Records. " Good Kisser" is a song by American singer Usher. From the album Hard II Love (Japanese edition) ![]() |
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